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A post-GWAS replication study confirming the association of

Shaohua YANG,Chao QI,Yan XIE,Xiaogang CUI,Yahui GAO,Jianping JIANG,Li JIANG,Shengli ZHANG,Qin ZHANG,Dongxiao SUN

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 4,   Pages 321-330 doi: 10.15302/J-FASE-2014037

Abstract: Among them, the gene is merely 87 bp away from the significant SNP, Hapmap30383-BTC-005848., we report herein genotype-phenotype associations to further validate the genetic effects of the geneBy pooled DNA sequencing of 14 unrelated Holstein sires, a total of 18 with seven novel SNPs were identified

Keywords： GWAS     functional annotation     Chinese Holstein     milk production traits     C14H8orf33 gene     single nucleotide    

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Gene therapy for hemophilia B mice with scAAV8-LP1-hFIX

Wei Lu,Qingzhang Zhou,Hao Yang,Hao Wang,Yexing Gu,Qi Shen,Jinglun Xue,Xiaoyan Dong,Jinzhong Chen

Frontiers of Medicine 2016, Volume 10, Issue 2,   Pages 212-218 doi: 10.1007/s11684-016-0438-y

Abstract: Gene therapy might be the ultimate strategy for the disease.However, two main problems that should be solved in gene therapy for hemophilia B are immunity and safetySelf-complementary adeno-associated virus serotype 8 (scAAV8), a non-human primate AAV featuring lowimmunogenicity and high transfection efficiency in liver cells, might be a potential vector for hemophilia B geneOur study provides a potential gene therapy method for hemophilia B.

Keywords： hemophilia B     AAV8     hFIX     gene therapy    

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Enhancing the efficiency of nitrogen removing bacterial population to a wide range of C:N ratio (1.5:1 to 14:1) for simultaneous C & N removal

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 8, doi: 10.1007/s11783-022-1522-y

Abstract:

• Simultaneous C & N removal in Methammox occurs at wide C:N ratio.

Keywords： Methanogens     Biological Nitrogen Removal (BNR)     Simultaneous     Methammox     C:N ratio    

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A rare case of B-lymphoproliferative disorder with villous lymphocytes harboring t(8;14)(q24;q32) translocation

Xiaofeng Shi, Rong Ba, Haiyan You, Qian Jiang, Jiansong Huang, Jianhua Mao, Lanxiu Han, Shuo Zhang, Qin Zhuang, Xianqiu Yu, Lixia Wang, Yun Wang, Dongya Li, Wei Zhu, Yong Zhang, Yan Zhu, Xiaodong Xi

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 324-329 doi: 10.1007/s11684-017-0558-z

Abstract: At present, only one case of SLVL with t(8;14)(q24;q32) translocation has been reported.>, CD7−, CD10−, CD23−, CD34−, CD33>−, CD103−, and CD11c−.The karyotype showed complex abnormality: 46XX,+3,−10, t(8;14)(q24;q32)[11]/46XX[9].nucleoli and high lymphocytosis suggested prolymphocytic transformation, probably as a result of t(8,14

Keywords： splenic lymphoma with villous lymphocytes     splenic marginal zone lymphoma     transformation     chromosome translocation    

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The Progress and Application of the SKI Series Catalysts for Isomerization of C8 Aromatics

Qiao Yingbin

Strategic Study of CAE 1999, Volume 1, Issue 1,   Pages 73-77

Abstract:

The innovative idea and excellent performance of the SKI series catalysts for isomerization of C8 aromatics are elaborated.The thermodynamic equilibrium can be approached for the isomerization of the mixed C8 aromaticsThe selectivity for the C8 aromatics is more than 97% and the catalyst life-span is more than

Keywords： isomerization     catalyst     xylene    

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A density functional theory study of methane activation on MgO supported NiM cluster: role of M on C–H

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 10,   Pages 1485-1492 doi: 10.1007/s11705-022-2169-8

Abstract: The role of M on the first C–H bond cleavage of CH4 was investigated.Doping elements of the same period in Ni cluster, such as Fe, Co and Cu, for C–H bond activation followsAs a result, Ni–Fe shows the best ability for C–H bond cleavage.Consequently, C–H bond activation demands a lower energy barrier on Ni–Pt cluster.

Keywords： CH4 dissociation     Ni–M     C–H bond activation     charge transfer    

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Robust Metal–Organic Frameworks with High Industrial Applicability in Efficient Recovery C3H8 and C2H6 from Natural Gas Upgrading Article

Shikai Xian, Junjie Peng, Haardik Pandey, Timo Thonhauser, Hao Wang, Jing Li

Engineering 2023, Volume 23, Issue 4,   Pages 56-63 doi: 10.1016/j.eng.2022.07.017

Abstract: sub>2H6 and C3H8 from natural gas is an important but challengingsub>3H8 and C2H6, giving rise to the high loading capacity andselectivity for C3H8 and C2H6.sub>3H8/C2H6/CH4 has been demonstrated by ternary breakthroughsub>2H6 and C3H8.

Keywords： Metal–     organic framework     Hydrocarbon adsorption and separation     Selectivity     Stability     Scale-up synthesis    

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significance of CD34+CD117dim/CD34+CD117bri myeloblast-associated geneexpression in t(8;21) acute myeloid leukemia

Xueping Li, Yuting Dai, Bing Chen, Jinyan Huang, Saijuan Chen, Lu Jiang

Frontiers of Medicine 2021, Volume 15, Issue 4,   Pages 608-620 doi: 10.1007/s11684-021-0836-7

Abstract: Here, we examined the impact of CD34 CD117 /CD34 CD117 myeloblast-associated gene expression on t(8;In this study, 85 patients with t(8;21) AML were enrolled.Associations between gene expression and clinical outcomes were determined using Cox regression modelsIdentifying the clinical relevance of CD34 CD117 /CD34 CD117 myeloblast-associated gene expression mayprovide new clinically prognostic markers for t(8;21) AML.

Keywords： t(8     21)(q22     q22) AML     CD34+CD117dim/ CD34+CD117bri cell population     gene expression     prognosis    

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MoS2/ZIF-8 Hybrid Materials for Environmental Catalysis: Solar-Driven Antibiotic-Degradation Article

Wen-Qian Chen, Linyue Li, Lin Li, Wen-Hui Qiu, Liang Tang, Ling Xu, Kejun Xu, Ming-Hong Wu

Engineering 2019, Volume 5, Issue 4,   Pages 755-767 doi: 10.1016/j.eng.2019.02.003

Abstract: In this paper, we demonstrate a MoS2/ZIF-8 composite photocatalyst that increases the photocatalyticThe hydrogen production rate of the MoS2/ZIF-8 nanocomposites is 1.79 times higher than thatThis work provides a novel perspective for exploring original and efficient 1T/2H-MoS2/MOF-basedThus, 1T/2H-MoS2/MOF-based photocatalysts have excellent prospects for practical antibiotic-degradation

Keywords： 1T/2H-MoS2     ZIF-8     Antibiotic degradation     Photocatalysis    

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Analysis of the double-layer α-Si:H emitter with different doping concentrations for α-Si:H/c-Si heterojunction

Haibin HUANG,Gangyu TIAN,Tao WANG,Chao GAO,Jiren YUAN,Zhihao YUE,Lang ZHOU

Frontiers in Energy 2017, Volume 11, Issue 1,   Pages 92-95 doi: 10.1007/s11708-016-0432-8

Abstract: concentrations (DLE) have been designed and prepared for amorphous silicon/crystalline silicon (α-Si:H/c-Si) heterojunction solar cells.

Keywords： double-layer emitter     α-Si:H/c-Si heterojunction solar cell     short circuit current     quantum efficiency     current-voltage-temperature    

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Homoharringtonine synergy with oridonin in treatment of t(8; 21) acute myeloid leukemia

Weina Zhang, Ying Lu, Tao Zhen, Xinjie Chen, Ming Zhang, Ping Liu, Xiangqin Weng, Bing Chen, Yueying Wang

Frontiers of Medicine 2019, Volume 13, Issue 3,   Pages 388-397 doi: 10.1007/s11684-018-0624-1

Abstract: Collaboration of c-KIT mutations with AML1–ETO (AE) has been demonstrated to induce t(8; 21) acute myeloidTargeted therapies designed to eliminate AE and c-KIT oncoproteins may facilitate effective treatmentof t(8; 21) AML.Homoharringtonine (HHT) features activity against tumor cells harboring c-KIT mutations, whereas oridoninOridonin and HHT induced significant downregulation of c-KIT and its downstream signaling pathways and

Keywords： AML1–ETO     c-KIT     homoharringtonine     oridonin     t(8     21) AML     synergistic effect    

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Modeling of alkali-silica reaction in concrete: a review

WANG, Q.C. SUN, C.H. ZHANG, D.R.J. OWEN

Frontiers of Structural and Civil Engineering 2012, Volume 6, Issue 1,   Pages 1-18 doi: 10.1007/s11709-012-0141-2

Abstract: This paper presents a comprehensive review of modeling of alkali-silica reaction (ASR) in concrete. Such modeling is essential for investigating the chemical expansion mechanism and the subsequent influence on the mechanical aspects of the material. The concept of ASR and the mechanism of expansion are first outlined, and the state-of-the-art of modeling for ASR, the focus of the paper, is then presented in detail. The modeling includes theoretical approaches, meso- and macroscopic models for ASR analysis. The theoretical approaches dealt with the chemical reaction mechanism and were used for predicting pessimum size of aggregate. Mesoscopic models have attempted to explain the mechanism of mechanical deterioration of ASR-affected concrete at material scale. The macroscopic models, chemo-mechanical coupling models, have been generally developed by combining the chemical reaction kinetics with linear or nonlinear mechanical constitutive, and were applied to reproduce and predict the long-term behavior of structures suffering from ASR. Finally, a conclusion and discussion of the modeling are given.

Keywords： alkali-silica reaction (ASR)     modeling     concrete     mesoscopic     macroscopic    

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Uncertainty propagation analysis by an extended sparse grid technique

JIA, C. JIANG, C. M. FU, B. Y. NI, C. S. WANG, M. H. PING

Frontiers of Mechanical Engineering 2019, Volume 14, Issue 1,   Pages 33-46 doi: 10.1007/s11465-018-0514-x

Abstract: In this paper, an uncertainty propagation analysis method is developed based on an extended sparse grid technique and maximum entropy principle, aiming at improving the solving accuracy of the high-order moments and hence the fitting accuracy of the probability density function (PDF) of the system response. The proposed method incorporates the extended Gauss integration into the uncertainty propagation analysis. Moreover, assisted by the Rosenblatt transformation, the various types of extended integration points are transformed into the extended Gauss-Hermite integration points, which makes the method suitable for any type of continuous distribution. Subsequently, within the sparse grid numerical integration framework, the statistical moments of the system response are obtained based on the transformed points. Furthermore, based on the maximum entropy principle, the obtained first four-order statistical moments are used to fit the PDF of the system response. Finally, three numerical examples are investigated to demonstrate the effectiveness of the proposed method, which includes two mathematical problems with explicit expressions and an engineering application with a black-box model.

Keywords： uncertainty propagation analysis     extended sparse grid     maximum entropy principle     extended Gauss integration     Rosenblatt transformation     high-order moments analysis    

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Plasma enhanced chemical vapor deposition of excellent a-Si:H passivation layers for a-Si:H/c-Si heterojunction

Lei ZHAO,Wenbin ZHANG,Jingwei CHEN,Hongwei DIAO,Qi WANG,Wenjing WANG

Frontiers in Energy 2017, Volume 11, Issue 1,   Pages 85-91 doi: 10.1007/s11708-016-0437-3

Abstract: The intrinsic a-Si:H passivation layer inserted between the doped a-Si:H layer and the c-Si substrateis very crucial for improving the performance of the a-Si:H/c-Si heterojunction (SHJ) solar cell.In this paper, intrinsic a-Si:H layers were prepared on n-type Cz c-Si substrates by 27.12 MHz PECVDThe corresponding passivation performance on c-Si was investigated by minority carrier lifetime measurementsolar cell with an efficiency of 22.25% was fabricated on the commercial 156 mm pseudo-square n-type Cz c-Si

Keywords： PECVD     high pressure and high power     a-Si:H microstructure     passivation     heterojunction solar cell    

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Liver surgery and transplantation in China: Progress and Challenges

LAU W Y, LAI E C H

Frontiers of Medicine 2007, Volume 1, Issue 1,   Pages 1-5 doi: 10.1007/s11684-007-0001-y

Abstract: From the limited but available information, we traced the history of developments of liver surgery and transplantation in China. Liver surgery first started in the late 1950s in China, and it soon flourished mainly because of the great demand in liver surgery and the emergence of a number of giants in liver surgery. We recognized and honoured the important contributions of these Chinese pioneers in portal hypertension, recurrent pyogenic cholangitis, hepatocellular carcinoma and liver transplantation.

Keywords： transplantation     pyogenic cholangitis     available information     important     hypertension    

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Title Author Date Type Operation

A post-GWAS replication study confirming the association of

Shaohua YANG,Chao QI,Yan XIE,Xiaogang CUI,Yahui GAO,Jianping JIANG,Li JIANG,Shengli ZHANG,Qin ZHANG,Dongxiao SUN

Journal Article

Gene therapy for hemophilia B mice with scAAV8-LP1-hFIX

Wei Lu,Qingzhang Zhou,Hao Yang,Hao Wang,Yexing Gu,Qi Shen,Jinglun Xue,Xiaoyan Dong,Jinzhong Chen

Journal Article

Enhancing the efficiency of nitrogen removing bacterial population to a wide range of C:N ratio (1.5:1 to 14:1) for simultaneous C & N removal

Journal Article

A rare case of B-lymphoproliferative disorder with villous lymphocytes harboring t(8;14)(q24;q32) translocation

Xiaofeng Shi, Rong Ba, Haiyan You, Qian Jiang, Jiansong Huang, Jianhua Mao, Lanxiu Han, Shuo Zhang, Qin Zhuang, Xianqiu Yu, Lixia Wang, Yun Wang, Dongya Li, Wei Zhu, Yong Zhang, Yan Zhu, Xiaodong Xi

Journal Article

The Progress and Application of the SKI Series Catalysts for Isomerization of C8 Aromatics

Qiao Yingbin

Journal Article

A density functional theory study of methane activation on MgO supported NiM cluster: role of M on C–H

Journal Article

Robust Metal–Organic Frameworks with High Industrial Applicability in Efficient Recovery C3H8 and C2H6 from Natural Gas Upgrading

Shikai Xian, Junjie Peng, Haardik Pandey, Timo Thonhauser, Hao Wang, Jing Li

Journal Article

significance of CD34+CD117dim/CD34+CD117bri myeloblast-associated geneexpression in t(8;21) acute myeloid leukemia

Xueping Li, Yuting Dai, Bing Chen, Jinyan Huang, Saijuan Chen, Lu Jiang

Journal Article

MoS2/ZIF-8 Hybrid Materials for Environmental Catalysis: Solar-Driven Antibiotic-Degradation

Wen-Qian Chen, Linyue Li, Lin Li, Wen-Hui Qiu, Liang Tang, Ling Xu, Kejun Xu, Ming-Hong Wu

Journal Article

Analysis of the double-layer α-Si:H emitter with different doping concentrations for α-Si:H/c-Si heterojunction

Haibin HUANG,Gangyu TIAN,Tao WANG,Chao GAO,Jiren YUAN,Zhihao YUE,Lang ZHOU

Journal Article

Homoharringtonine synergy with oridonin in treatment of t(8; 21) acute myeloid leukemia

Weina Zhang, Ying Lu, Tao Zhen, Xinjie Chen, Ming Zhang, Ping Liu, Xiangqin Weng, Bing Chen, Yueying Wang

Journal Article

Modeling of alkali-silica reaction in concrete: a review

WANG, Q.C. SUN, C.H. ZHANG, D.R.J. OWEN

Journal Article

Uncertainty propagation analysis by an extended sparse grid technique

JIA, C. JIANG, C. M. FU, B. Y. NI, C. S. WANG, M. H. PING

Journal Article

Plasma enhanced chemical vapor deposition of excellent a-Si:H passivation layers for a-Si:H/c-Si heterojunction

Lei ZHAO,Wenbin ZHANG,Jingwei CHEN,Hongwei DIAO,Qi WANG,Wenjing WANG

Journal Article

Liver surgery and transplantation in China: Progress and Challenges

LAU W Y, LAI E C H

Journal Article